Cervicovaginal fluid cytokines as predictive markers of preterm birth in symptomatic women
نویسندگان
چکیده
منابع مشابه
Cervicovaginal Fluid Acetate: A Metabolite Marker of Preterm Birth in Symptomatic Pregnant Women
Changes in vaginal microbiota that is associated with preterm birth (PTB) leave specific metabolite fingerprints that can be detected in the cervicovaginal fluid (CVF) using metabolomics techniques. In this study, we characterize and validate the CVF metabolite profile of pregnant women presenting with symptoms of threatened preterm labor (PTL) by both 1H-nuclear magnetic resonance spectroscopy...
متن کاملBiochemical Markers of Spontaneous Preterm Birth in Asymptomatic Women
Preterm birth is a delivery that occurs at less than 37 completed weeks of gestation and it is associated with perinatal morbidity and mortality. Spontaneous preterm birth accounts for up to 75% of all preterm births. A number of maternal or fetal characteristics have been associated with preterm birth, but the use of individual or group biochemical markers have advanced some of the understandi...
متن کاملMetabolite Profile of Cervicovaginal Fluids from Early Pregnancy Is Not Predictive of Spontaneous Preterm Birth.
In our study, we used a mass spectrometry-based metabolomic approach to search for biomarkers that may act as early indicators of spontaneous preterm birth (sPTB). Samples were selected as a nested case-control study from the Screening for Pregnancy Endpoints (SCOPE) biobank in Auckland, New Zealand. Cervicovaginal swabs were collected at 20 weeks from women who were originally assessed as bein...
متن کاملCervical interleukin-6 as a predictive test for preterm delivery in symptomatic women: preliminary results.
OBJECTIVE The aim of this study is to assess the efficacy of cervical interleukin-6 (IL-6) compared with cervical length and its association in the prediction of preterm delivery in symptomatic women. STUDY DESIGN Observational prospective study was performed at Hospital Universitario La Fe, Valencia (Spain). SAMPLE 100 women between 24 and 34 weeks gestational age, with threatened preterm ...
متن کاملDiagnostic accuracy of cervicovaginal interleukin-6 and interleukin-6:albumin ratio as markers of preterm delivery.
BACKGROUND Absence of fetal fibronectin (fFN) in the cervicovaginal fluid (CVF) of women with symptoms of preterm labor is an excellent predictor of women who will not deliver within 2 weeks of testing. Preliminary studies suggest interleukin (IL)-6 performs similarly to fFN. The positive predictive values of both these assays are poor. Inconsistent specimen collection may explain this poor per...
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ژورنال
عنوان ژورنال: Obstetrics & Gynecology Science
سال: 2020
ISSN: 2287-8572,2287-8580
DOI: 10.5468/ogs.19131